Monday, January 28, 2013

'Hansel & Gretel' fetches No. 1 at box office

LOS ANGELES (AP) ? "Hansel & Gretel: Witch Hunters" cooked up $19 million in its opening weekend.

The action film update on the classic children's tale starring Jeremy Renner and Gemma Arterton topped the box office, according to studio estimates Sunday.

The supernatural horror film "Mama" starring Jessica Chastain landed in second place with $12.8 million in its second weekend.

Academy Awards contender "Sliver Linings Playbook" featuring Bradley Cooper and Jennifer Lawrence came in third place with $10 million.

The action film "Parker" starring Jason Statham and Jennifer Lopez opened in fifth place with $7 million, while the raunchy comedy "Movie 43" debuted in the seventh spot with $5 million.

Source: http://news.yahoo.com/hansel-gretel-fetches-no-1-box-office-180009705.html

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Poor sleep in old age prevents the brain from storing memories

Jan. 27, 2013 ? The connection between poor sleep, memory loss and brain deterioration as we grow older has been elusive. But for the first time, scientists at the University of California, Berkeley, have found a link between these hallmark maladies of old age. Their discovery opens the door to boosting the quality of sleep in elderly people to improve memory.

Postdoctoral fellow, Bryce Mander, demonstrates how the sleep study was conducted.

UC Berkeley neuroscientists have found that the slow brain waves generated during the deep, restorative sleep we typically experience in youth play a key role in transporting memories from the hippocampus -- which provides short-term storage for memories -- to the prefrontal cortex's longer term "hard drive."

However, in older adults, memories may be getting stuck in the hippocampus due to the poor quality of deep 'slow wave' sleep, and are then overwritten by new memories, the findings suggest.

"What we have discovered is a dysfunctional pathway that helps explain the relationship between brain deterioration, sleep disruption and memory loss as we get older -- and with that, a potentially new treatment avenue," said UC Berkeley sleep researcher Matthew Walker, an associate professor of psychology and neuroscience at UC Berkeley and senior author of the study to be published Jan. 27, in the journal Nature Neuroscience.

The findings shed new light on some of the forgetfulness common to the elderly that includes difficulty remembering people's names.

"When we are young, we have deep sleep that helps the brain store and retain new facts and information," Walker said. "But as we get older, the quality of our sleep deteriorates and prevents those memories from being saved by the brain at night."

Healthy adults typically spend one-quarter of the night in deep, non-rapid-eye-movement (REM) sleep. Slow waves are generated by the brain's middle frontal lobe. Deterioration of this frontal region of the brain in elderly people is linked to their failure to generate deep sleep, the study found.

The discovery that slow waves in the frontal brain help strengthen memories paves the way for therapeutic treatments for memory loss in the elderly, such as transcranial direct current stimulation or pharmaceutical remedies. For example, in an earlier study, neuroscientists in Germany successfully used electrical stimulation of the brain in young adults to enhance deep sleep and doubled their overnight memory.

UC Berkeley researchers will be conducting a similar sleep-enhancing study in older adults to see if it will improve their overnight memory. "Can you jumpstart slow wave sleep and help people remember their lives and memories better? It's an exciting possibility," said Bryce Mander, a postdoctoral fellow in psychology at UC Berkeley and lead author of this latest study.

For the UC Berkeley study, Mander and fellow researchers tested the memory of 18 healthy young adults (mostly in their 20s) and 15 healthy older adults (mostly in their 70s) after a full night's sleep. Before going to bed, participants learned and were tested on 120 word sets that taxed their memories.

As they slept, an electroencephalographic (EEG) machine measured their brain wave activity. The next morning, they were tested again on the word pairs, but this time while undergoing functional and structural Magnetic Resonance Imaging (fMRI) scans.

In older adults, the results showed a clear link between the degree of brain deterioration in the middle frontal lobe and the severity of impaired "slow wave activity" during sleep. On average, the quality of their deep sleep was 75 percent lower than that of the younger participants, and their memory of the word pairs the next day was 55 percent worse.

Meanwhile, in younger adults, brain scans showed that deep sleep had efficiently helped to shift their memories from the short-term storage of the hippocampus to the long-term storage of the prefrontal cortex.

Co-authors of the study are William Jagust, Vikram Rao, Jared Saletin and John Lindquist of UC Berkeley; Brandon Lu of the California Pacific Medical Center and Sonia Ancoli-Israel of UC San Diego.

The research was funded by the National Institute of Aging of the National Institutes of Health.

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Story Source:

The above story is reprinted from materials provided by University of California - Berkeley. The original article was written by Yasmin Anwar.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Bryce A Mander, Vikram Rao, Brandon Lu, Jared M Saletin, John R Lindquist, Sonia Ancoli-Israel, William Jagust, Matthew P Walker. Prefrontal atrophy, disrupted NREM slow waves and impaired hippocampal-dependent memory in aging. Nature Neuroscience, 2013; DOI: 10.1038/nn.3324

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/mPkLDBVS1dI/130127134212.htm

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Market Chatter-Corporate finance press digest

Jan 28 (Reuters) - The following corporate finance-related

stories were reported by media on Monday:

* Internal reviews by banks in Singapore have found evidence

that traders colluded to manipulate rates in the offshore

foreign exchange market, according to a source with knowledge of

the inquiries.

* Bank of America has begun moving $50 billion of

derivatives out of its Irish-based operations into its British

subsidiary, The Financial Times reported.

* Barclays and Credit Suisse are both

preparing collateralised loan obligations - which bundle

corporate loans primarily for leveraged buyouts into a single

vehicle - for investment groups Pramerica and Cairn Capital,

said sources close to the deals. ()

* British insurer Admiral plans to buy law firm

Lyons Davidson to limit the financial impact of a ban on lawyers

paying for accident victims' contact details, the Mail on Sunday

reported, citing an unnamed source.

* BlackRock, the world's largest asset management

company, has taken an $80 million stake in Twitter Inc, a person

with knowledge of the deal said.

* Indonesia-focused miner Bumi Plc will announce

plans for a smaller board and a new company name as it seeks to

break with two years of damaging battles between investors, a

source familiar with the matter said.

Source: http://news.yahoo.com/market-chatter-corporate-finance-press-digest-041345754--sector.html

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Quit Smoking by 40, Live Long and Prosper: Study | Food, Health ...


Good news for those trying to snuff out their smoking habit: in a new study, smokers who quit before turning 40 regained all of the years they would have presumably lost if they continued smoking.

Smoking cuts at least 10 years off a person?s lifespan, at least according to research. But a comprehensive analysis of health and death records in the US suggests that the damage isn?t permanent, as long as you quit.

?Quitting smoking before age 40, and preferably well before 40, gives back almost all of the decades of lost life from continued smoking,? says Dr. Prabhat Jha, head of the Centre for Global Health Research at St. Michael?s Hospital and a professor in the Dalla Lana School of Public Health at the University of Toronto.

?That?s not to say, however, that it is safe to smoke until you are 40 and then stop,? Jha adds. ?Former smokers still have a greater risk of dying sooner than people who never smoked. But the risk is small compared to the huge risk for those who continue to smoke.?

Continue reading at Yahoo!She

Tagged smoking

Source: http://allfoodnutrition.net/4879-quit-smoking-40-live-long-prosper.html

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Wednesday, January 23, 2013

Tuesday, January 22, 2013

Is Facebook envy making you miserable?

LONDON (Reuters) - Witnessing friends' vacations, love lives and work successes on Facebook can cause envy and trigger feelings of misery and loneliness, according to German researchers.

A study conducted jointly by two German universities found rampant envy on Facebook, the world's largest social network that now has over one billion users and has produced an unprecedented platform for social comparison.

The researchers found that one in three people felt worse after visiting the site and more dissatisfied with their lives, while people who browsed without contributing were affected the most.

"We were surprised by how many people have a negative experience from Facebook with envy leaving them feeling lonely, frustrated or angry," researcher Hanna Krasnova from the Institute of Information Systems at Berlin's Humboldt University told Reuters.

"From our observations some of these people will then leave Facebook or at least reduce their use of the site," said Krasnova, adding to speculation that Facebook could be reaching saturation point in some markets.

Researchers from Humboldt University and from Darmstadt's Technical University found vacation photos were the biggest cause of resentment with more than half of envy incidents triggered by holiday snaps on Facebook.

Social interaction was the second most common cause of envy as users could compare how many birthday greetings they received to those of their Facebook friends and how many "likes" or comments were made on photos and postings.

"Passive following triggers invidious emotions, with users mainly envying happiness of others, the way others spend their vacations and socialize," the researchers said in the report "Envy on Facebook: A Hidden Threat to Users' Life Satisfaction?" released on Tuesday.

"The spread and ubiquitous presence of envy on Social Networking Sites is shown to undermine users' life satisfaction."

They found people aged in their mid-30s were most likely to envy family happiness while women were more likely to envy physical attractiveness.

These feelings of envy were found to prompt some users to boast more about their achievements on the site run by Facebook Inc. to portray themselves in a better light.

Men were shown to post more self-promotional content on Facebook to let people know about their accomplishments while women stressed their good looks and social lives.

The researchers based their findings on two studies involving 600 people with the results to be presented at a conference on information systems in Germany in February.

The first study looked at the scale, scope and nature of envy incidents triggered by Facebook and the second at how envy was linked to passive use of Facebook and life satisfaction.

The researchers said the respondents in both studies were German but they expected the findings to hold internationally as envy is a universal feeling and possibly impact Facebook usage.

"From a provider's perspective, our findings signal that users frequently perceive Facebook as a stressful environment, which may, in the long-run, endanger platform sustainability," the researchers concluded.

(Reporting by Belinda Goldsmith, editing by Paul Casciato)

Source: http://news.yahoo.com/facebook-envy-making-miserable-154820957--finance.html

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Let Go of the Ego of Ownership - Slow Your Home

"consume less; share better"

?Did you know that the average domestic power drill is used for less than one hour over its entire lifespan?

You need the hole, not the drill!?

? Rachel Botsman, TED Talk 2012

Imagine the resources used in producing that drill ? the man-hours, energy, shipping and packaging, not to mention the potentially unfair work conditions in the developing country that manufactures the drill. All for less than one hour of use over two, three ? maybe ten years.

What if, instead of owning one of everything we occasionally?need, we adopted a culture of sharing? A co-operative attitude of non-ownership? Of shared ownership?

Imagine the savings:

  • save money simply by not needing to buy every occasional-use item
  • save storage space by not needing the room to keep all of these items
  • decrease your environmental impact by not buying items you don?t need to own

Sure. But That?s Pretty Inconvenient.

Maybe driving to a friend?s house to borrow a drill ? when you only need one hole ? is inconvenient. But how did we get into this financial/environmental/hyper-consumerism mess in the first place? By buying reflexively instead of looking for alternatives, instead of experiencing a little inconvenience, instead of calling a friend and asking to borrow a drill.

Your actions have consequences. Weigh up inconvenience vs negative impact and ask yourself if there is a better alternative.

Shared Ownership ? It is Possible.

Without realising it, my family have been long-time sharers. For years, my mum?s side of the family have had a ?party box? of cutlery. There was enough for 100 people and anytime someone had a party, the box was there. I don?t even know who owned it, but I do know that one box of cutlery stopped countless uneccessary purchases and even more uneccessary waste.

No-one had to buy extra cutlery when entertaining ? you just borrowed the party box. No-one had to use disposable cutlery ? you just borrowed the party box. Everyone benefited.

We also share power tools, trestle tables for parties and gatherings, extra chairs, toys, baby clothes, camping gear, crockery, serving platters, wine glasses and linens.

Most of these are not everyday items. Which is why it works so well. But just consider the possibilities of sharing, if you pooled resources with your nearby friends, family and neighbours.

You could share your:

  • power tools
  • lawnmower
  • car (there are many car-sharing options now ? which don?t work for everyone, I admit. But it?s worth considering if you live in an urban area)
  • party needs ? extra tables, chairs, cutlery, crockery and wine glasses
  • toys
  • fabric nappies
  • baby items ? rockers, prams, bassinet
  • extra linen and bedding for guests
  • surfboards, snowboards and ski gear
  • DIY equipment ? ladder, painting gear, dropsheets
  • luggage ? suitcases, backpacks
  • hiking gear
  • skills
  • knowledge

Go Against the Grain.

Sharing these things runs counter to what we?ve always done. Surely someone who has to borrow a drill, a mattress, toys or a suitcase is doing something wrong? Successful people don?t need to borrow things ? they own them. And if they don?t, they can certainly go out and buy them.

But it?s time to turn that thinking on its head. It?s time to own less and be open to sharing. It?s time to let go of the ego that comes with ?having everything you need?.

It?s time to pool our resources, before we deplete the earth of its resources completely.

But sharing only works if:

  • everyone contributes ? by borrowing from others, you need to be OK with lending your belongings to them in return
  • borrowed items are respected and returned ? it?s not an excuse to keep things for months on end or treat them poorly
  • there is trust ? if you?re constantly concerned that someone will steal your belongings, then you?re probably sharing with the wrong people
  • you plan ahead ? it will prove too inconvenient if you wait until the last minute to borrow what you need
  • you talk it through with your friends, family and neighbours ? there?s no point in having a one-way agreement that only you are aware of.

Create Your Own Movement

Talk to your friends and family about starting a co-op. Float the idea with like-minded people to begin with and talk about the benefits ? financial, environmental and social. Give it a test-run for a month or two and then be open to changes. Expand your network of members if it?s going well. Talk over any problems if it?s not.

And if you don?t have nearby friends and family to share with, then consider starting your own community co-op.

It doesn?t have to be complicated ? start by posting a notice in the newspaper or establishing a group on Facebook. Each member needs to be willing to share their occasional-use items and be happy to borrow from others. Keep a list of what people are happy to lend and let members contact each other when they need to borrow an item.

?

We need to shift priorities. It?s no longer about proving our personal success by showcasing all that we own.

It?s about removing the ego, stripping away the importance of personal ownership, and looking for a better alternative.

?

Do you think this movement of shared ownership could work in your circle of friends and family?

?

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Source: http://www.slowyourhome.com/2013/01/22/let-go-of-the-ego-of-ownership/

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Is Twitter Completely Down for You?

Twitter is having big time problems in some places right now. Out in California, I can't even get the website to load or the desktop app to show any tweets. It's completely, utterly borked. But out in New York, no one seems to be having any problems. And Twitter on my phone works! What's the deal? More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/_JkGgGjtLDg/is-twitter-completely-down-for-you

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Monday, January 21, 2013

Second Term: Obama says now is the time to act

President Barack Obama and first lady Michelle Obama waves as they walk down Pennsylvania Avenue near the White House during the 57th Presidential Inauguration parade Monday, Jan. 21, 2013, in Washington. (AP Photo/Charles Dharapak)

President Barack Obama and first lady Michelle Obama waves as they walk down Pennsylvania Avenue near the White House during the 57th Presidential Inauguration parade Monday, Jan. 21, 2013, in Washington. (AP Photo/Charles Dharapak)

President Barack Obama and first lady Michelle Obama walk the inaugural parade route walk down Pennsylvania Avenue en route to the White House, Monday, Jan. 21, 2013, in Washington. Thousands marched during the 57th Presidential Inauguration parade after the ceremonial swearing-in of President Barack Obama. (AP Photo/Gerald Herbert)

President Barack Obama and first lady Michelle Obama walk the inaugural parade route down Pennsylvania Avenue en route to the White House, Monday, Jan. 21, 2013, in Washington. Thousands marched during the 57th Presidential Inauguration parade after the ceremonial swearing-in of President Barack Obama. (AP Photo/Charlie Neibergall)

President Barack Obama waves after his speech while Vice President Joe Biden applauds at the ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013. (AP Photo/Pablo Martinez Monsivais)

President Barack Obama, followed by US Army Maj. Gen. Michael J. Linnington waves on Capitol Hill in Washington, Monday, Jan. 21, 2013, after the Presidential review of the troops on the east side of the Capitol following his Inaugural address and ceremonial swearing-in ceremony during the 57th Presidential Inauguration. (AP Photo/CJ Gunther, Pool)

(AP) ? Turning the page on years of war and recession, President Barack Obama summoned a divided nation Monday to act with "passion and dedication" to broaden equality and prosperity at home, nurture democracy around the world and combat global warming for generations to come as he embarked on a second term before a vast and cheering crowd that spilled down the historic National Mall.

"America's possibilities are limitless, for we possess all the qualities that this world without boundaries demands," the 44th president declared in a second inaugural address that broke new ground by assigning gay rights a prominent place in the wider struggle for equality for all.

In a unity plea to politicians and the nation at large, he called for "collective action" to confront challenges and said, "Progress does not compel us to settle centuries-long debates about the role of government for all time ? but it does require us to act in our time."

Elected four years ago as America's first black president, Obama spoke from specially constructed flag-bedecked stands outside the Capitol after reciting oath of office that all presidents have uttered since the nation's founding.

The events highlighted a day replete with all the fanfare that a security-minded capital could muster ? from white-gloved Marine trumpeters who heralded the arrival of dignitaries on the inaugural stands to the mid-winter orange flowers that graced the tables at a traditional lunch with lawmakers inside the Capitol.

The weather was relatively warm, in the mid-40s, and while the crowd was not as large as on Inauguration Day four years ago, it was counted in the hundreds of thousands.

Big enough that he turned around as he was leaving the inaugural stands to savor the view one final time.

"I'm not going to see this again," said the man whose political career has been meteoric ? from the Illinois Legislature to the U.S. Senate and the White House before marking his 48th birthday.

On a day of renewal for democracy, everyone seemed to have an opinion, and many seemed eager to share it.

"I'm just thankful that we've got another four years of democracy that everyone can grow in," said Wilbur Cole, 52, a postman from suburban Memphis, Tenn., who spent part of the day visiting the civil rights museum there at the site where the Rev. Martin Luther King Jr. was assassinated in 1968. The inauguration this year shared the day with King's birthday holiday.

Less upbeat, Frank Pinto, 62, watched on television at a bar in Hartford, Conn., as the president was sworn in and spoke. An unemployed construction contractor, he said that because of Obama's policies, "My grandkids will be in debt and their kids will be in debt."

The tone was less overtly political in the nation's capital, where bipartisanship was on the menu in the speechmaking and at the congressional lunch.

"Congratulations and Godspeed," House Speaker John Boehner, a Republican, said to Obama and Vice President Joe Biden as he presented them with flags that had flown atop the Capitol.

Outside, the Inaugural Parade took shape, a reflection of American musicality and diversity that featured military units, bands, floats, the Chinese American Community Center Folk Dance Troupe from Hockessin, Del., and the Isiserettes Drill & Drum Corps from Des Moines, Iowa.

The crowds were several rows deep along parts of the route, and security was intense. More than a dozen vehicles flanked the president's limousine as it rolled down Pennsylvania Avenue, and several agents walked alongside on foot.

As recent predecessors have, the president emerged from his car and walked several blocks on foot. His wife, Michelle, was with him, and the two held hands while acknowledging the cheers from well-wishers during two separate strolls along the route.

In his brief, 18-minute speech, Obama did not dwell on the most pressing challenges of the past four years. He barely mentioned the struggle to reduce the federal deficit, a fight that has occupied much of his and Congress' time and promises the same in months to come.

He spoke up for the poor ? "Our country cannot succeed when a shrinking few do very well and a growing many barely make it" ? and for those on the next-higher rung ? "We believe that America's prosperity must rest upon the broad shoulders of a rising middle class." The second reference echoed his calls from the presidential campaign that catapulted him to re-election

"A decade of war is now ending. An economic recovery has begun," said the president who presided over the end to the U.S. combat role in Iraq, set a timetable for doing the same in Afghanistan and took office when the worst recession in decades was still deepening.

"We will support democracy from Asia to Africa, from the Americas to the Middle East, because our interests and our conscience compel us to act on behalf of those who long for freedom," he said in a relatively brief reference to foreign policy.

The former community organizer made it clear he views government as an engine of progress. While that was far from surprising for a Democrat, his emphasis on the need to combat global climate change was unexpected, as was his firm new declaration of support for full gay rights.

In a jab at climate-change doubters, he said, "Some may still deny the overwhelming judgment of science, but none can avoid the devastating impact of raging fires and crippling drought and more powerful storms." He said America must lead in the transition to sustainable energy resources.

He likened the struggle for gay rights to earlier crusades for women's suffrage and racial equality.

"Our journey is not complete until our gay brothers and sisters are treated like anyone else under the law ? for if we are truly created equal, then surely the love we commit to one another must be equal as well," said the president, who waited until his campaign for re-election last year to announce his support for gay marriage.

His speech hinted only barely at issues likely to spark opposition from Republicans who hold power in the House.

He defended Medicare, Medicaid and Social Security as programs that "do not make us a nation of takers; they free is to take the risks that made this country great."

He referred briefly to making "the hard choices to reduce the cost of health care and the size of our deficit," a rhetorical bow to a looming debate in which Republicans are seeking spending cuts in health care programs to slow the rise in a $16.4 trillion national debt.

He also cited a need for legislation to ease access to voting, an issue of particular concern to minority groups, and to immigration reform and gun-control legislation that he is expected to go into at length in his State of the Union speech on Feb. 12.

But his speech was less a list of legislative proposals than a plea for tackling challenges.

"We must act, knowing that our work will be imperfect," he said, and today's "victories will only be partial."

There was some official business conducted during the day.

Moments after being sworn in, the president signed nomination papers for four new appointees to his Cabinet, Sen. John Kerry for secretary of state, White House chief of staff Jacob Lew to be treasury secretary, former Nebraska Sen. Chuck Hagel for defense secretary and White House adviser John Brennan to head the CIA.

___

Associated Press writers Larry Margasak, Darlene Superville, Donna Cassata, Alan Fram, Andrew Taylor, Stephen Ohlemacher, Jim Kuhnhenn, Julie Pace, Tom Ritchie and Tracy Brown, in Washington; Adrian Santz in Memphis, Tenn., and Stephen Singer in Hartford, Conn., contributed to this story.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-01-21-Obama-Inauguration/id-a30111e25b154adf84744f6acee6d674

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Olympic medalist Michelle Kwan marries in RI

In this photo Jan. 19, 2013, Olympic skater, Michelle Kwan and Coast Guard Lt. Clay Pell leave the First Unitarian Church on Benefit Street after a wedding ceremony, in Providence, R.I. Kwan and Pell, a grandson of the late Sen. Claiborne Pell, have married in Rhode Island (AP Photo/Providence Journal, Frieda Squires)

In this photo Jan. 19, 2013, Olympic skater, Michelle Kwan and Coast Guard Lt. Clay Pell leave the First Unitarian Church on Benefit Street after a wedding ceremony, in Providence, R.I. Kwan and Pell, a grandson of the late Sen. Claiborne Pell, have married in Rhode Island (AP Photo/Providence Journal, Frieda Squires)

PROVIDENCE, R.I. (AP) ? Olympic medalist figure skater Michelle Kwan and a grandson of the late U.S. Sen. Claiborne Pell have married in Rhode Island.

The Providence Journal reports (http://bit.ly/VCCver ) Kwan and Coast Guard Lt. Clay Pell married at the First Unitarian Church in Providence. About 250 guests attended, including Gov. Lincoln Chafee (CHAY'-fee) and his wife.

Uniformed police officers stood guard outside the church Saturday as the 32-year-old Kwan and her bridesmaid emerged from a club across the street.

Kwan is a public policy envoy with the Department of State and the most decorated figure skater in American history. She won 43 championships, the silver medal at the 1998 Winter Olympics and bronze at the 2002 Games.

Pell works on the national security staff at the White House.

___

Information from: The Providence Journal, http://www.providencejournal.com

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-01-20-Kwan-Pell%20Marriage/id-844fb9e1e36f499a8adecf13493b7207

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SOME OPPOSITION

Two signs held by people on Pennsylvania Avenue going toward the Capitol: "God Hates Obama" and "America Is Doomed."

? Darlene Superville ? Twitter http://twitter.com/dsupervilleap

___

Inauguration Watch follows the events of President Barack Obama's second inaugural. Look for short items and photos throughout the day.

Source: http://news.yahoo.com/opposition-160205469.html

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Thursday, January 10, 2013

Drug resistance: 'Baby steps' can pay off big

Thursday, January 10, 2013

Rice University scientists have found that mutations of small effect can turn out to be game changers in the bacterial fight against antibiotic drugs.

The discovery came during an exhaustive, three-year effort to create a mathematical model that could accurately predict how specific mutations allow bacteria like E. coli to adapt to antibiotics like minocycline. The findings are detailed in a Dec. 10 study in the Proceedings of the National Academy of Sciences.

"As biologists, we tend to focus on big effects that result from big changes, but this study shows that bacteria don't have to solve the problem of antibiotic resistance in one giant step," said Rice University biochemist Yousif Shamoo, the lead researcher on a new study. "We were surprised to see that small mutations could make a big difference. In some cases, we saw that minor molecular changes could boost resistance by as much as 500 percent."

Despite the remarkable success of antibiotics, bacterial infections remain a leading cause of death, and antibiotic resistance among bacterial pathogens is a significant threat to public health.

Shamoo, professor of biochemistry and cell biology and director of Rice's Institute of Biosciences and Bioengineering, said the study of antibiotic resistance offers opportunities to both examine complex cellular phenomena and address the "genotype to phenotype problem," one of modern biology's major challenges.

"We've sequenced hundreds of genomes, and we're finding that it's one thing to read the blueprint, and it's another thing to predict how the DNA in that blueprint will affect change in a living cell," Shamoo said.

Shamoo said that because a single antibiotic resistance gene can make big changes in whether a cell lives or dies, it is possible to make the connection between the gene and the cell's fitness to its environment.

To show that a mathematical model could accurately predict how specific mutations would affect E. coli resistance, Shamoo's team examined a gene called TetX2. The gene encodes an enzyme that inactivates the antibiotic minocycline. The researchers looked at the most likely mutations of the gene and found seven that led to increased antibiotic resistance. They then spent two years amassing a catalog of basic biochemical measurements for each mutant.

"If this organism were a car, then these enzymatic measurements would be the equivalent of things like the cubic displacement of the engine, the torque and so on," Shamoo said. "These are measurable variables, but by themselves they won't tell you the car's top speed or how fast it can accelerate from 0 to 60 (miles per hour)."

By measuring the performance improvements from each of the seven TetX2 mutants, the group was able to build a mathematical formula that accurately correlated the E. coli resistance with enzyme performance. To test the formula, the team measured the resistance of a new family of mutants and used the formula to calculate their enzyme performance metrics.

"Using the car analogy again, it's like we took one car and measured its top speed and acceleration using seven different engines," Shamoo said. "Then, we took the same car with an unknown engine and showed that we didn't have to open the hood and look to tell what kind of engine it had. We could tell that strictly by knowing its top speed and acceleration." By knowing how the car with the unknown engine performed on the race track, we could describe the engine without ever popping the hood and vice versa.

Shamoo said the research could lead to faster screening methods for resistant strains of bacteria, but the most immediate benefit is an improved understanding of how resistance develops.

"An example of that is this finding about the small steps," he said. "That was unexpected, and it tells us something fundamental about how resistance evolves. We still know that big changes can confer big benefits, but now we know that small changes can yield big benefits too. This tells us that we may need to look at things we might have overlooked in the past."

###

Rice University: http://media.rice.edu

Thanks to Rice University for this article.

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Source: http://www.labspaces.net/126223/Drug_resistance___Baby_steps__can_pay_off_big

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Sunday, January 6, 2013

Samsung's 2013 Digital Audio Lineup: Old Meets New (Meets Bluetooth)

Samsung's just announced its 2013 lineup of home theater and audio devices. The new set features an interesting mix of vintage and developing technologies designed to combine classic sound with modern connectivity. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/PhkmfpB0I5Q/samsung-announces-its-2013-digital-audio-lineup

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Saturday, January 5, 2013

How to Reach Your Ultimate Potential With Self Help Subliminal Audio

It is stated that we use less than 10% of the potential of our brains throughout daily life. Even the most talented amongst us rarely use more than this. Imagine what our lives and our world would be like if we were able to boost our mental capacity by just a few %. It is often claimed that as a species we use below 10% of our mental faculties, perhaps we are only a small fraction of the species we will develop into one day, and it is hard to imagine that if we only use 10% of our possible brain power now what we?d be like and capable of if we used just 20-30% !

In many ways our brains are so resourceful, and as we grow and develop we all progress in different ways. We are all shaped differently and use our brains in different ways, some people for example have a positive experience in school and go on to study increasingly more. Others revel in sports, they receive constructive praise for their sporting achievements and continue to practice ? on the way developing the proper mindset and patterns of thinking required for sports success.

Sadly, people also receive negative feedback ? being told they are no good academically, or that they will never flourish in a specific area. Just as our brains store positive feedback and reactions and shape our lives, they do the same with negative feedback too. Some neuro pathways close down and others open up, but essentially we limit our own potential. This is a form of self protection by our brains ? it stops you against experiencing the rejection and criticism again, and this is natural, but unfortunately it limits our potential too..

These self beliefs and patterns of thinking just become part of our personality, of who we are, and in the end they hold us back and actually stop us from reaching our full potential. However, ultimately you are still in control of your mind and you actually have the ability to take control and change your thoughts, beliefs, and things like your self esteem and base levels of confidence.

How?

Subliminals target your limiting beliefs, progressively break them down, and replace them with positive ones. Because they access your unconscious mind they can make changes where other regular ways of development fall short, and even when you are not consciously conscious of the messages they progressively build to shape your mind in a constructive way.

Subliminal audio has nearly limitless possibilities, from enhancing your capability to develop the ability to think positive to enhancing your social abilities.

Imagine if you were free of adverse beliefs, if you were blessed with a natural abundance of self confidence, imagine how much more you could achieve.

This doesn?t have to be a fantasy forever, it is certainly possible to develop your subconscious mind, rewire your mind and shape your life in lots of various ways, and you can get started today with the power of subliminal messages:

Visit http://www.online-ebook-download.com and Download These Unique 3 FREE Subliminal Audio Albums Today.
Article Source: http://www.articlealley.com/http://raffiray.articlealley.com/how-to-reach-your-ultimate-potential-with-self-help-subliminal-audio-1766223.html

Source: http://makingalife.org/abundance-prosperity/how-to-reach-your-ultimate-potential-with-self-help-subliminal-audio/

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The Short Story, The Class Room, and Ned Directions Forward ...

The Los Angles Review of Books has an excellent review of?David Shields and Matthew Vollmer?s Fakes: An Anthology of Pseudo-Interviews, Faux-Lectures, Quasi-Letters, ?Found? Texts, and Other Fraudulent Artifacts. What is so interesting about (in addition to the book itself) is the author,?Johannes Lichtman,?goes into some detail about the foundational text books of the MFA scene, how they have shaped writing and how this book may too, for good and bad. As I?m always interested in how the short story is developed I found it quite interesting. I?m less and less inclined to like the MFA experience of teaching writing. I didn?t get an MFA, but I can remember my undergrad days and the heavy Carver influence running through the whole thing.

AS MOST PEOPLE KNOW, it?s not easy to make money writing. Young writers read of a mythical past when aspiring authors could work for ?newspapers? in exotic locales like Kansas City, but even if there is still a newspaper operating out of some soon-to-be-abandoned warehouse on the banks of the Missouri, I bet it isn?t hiring. The BFA/MFA track has become one of the last refuges for young writers before they start fighting their way into the welfare state of grants and fellowships, and even if we remain undecided on the question of whether writing can be taught ? if I have to read another essay asking that question I may run away to Kansas City myself ? we have definitively declared that the teaching and learning of creative writing can be a good way to make money (or at least to postpone the need to do so).

For this reason, contemporary fiction anthologies have never been more proliferant than they are now. Classroom texts ? most often either the Scribner Anthology of Contemporary Fiction edited by Lex Williford and Michael Martone or the Vintage Book of Short Stories edited by Tobias Wolff ? are where many undergraduate writers (weaned on high school classics, Stephen King, Stephanie Meyer, and Chuck Palahniuk) get their first doses of modern short fiction. These books answer the burning question: what are real writers writing today?

Which makes it such a shame that the two most popular anthologies offer such limited answers. The Vintage and Scriber collections feature eleven writers in common, but more importantly, they draw from a common aesthetic. Both favor a kind of story that generally relies on a first page/first sentence hook, a second page circling back to explain how we came to this interesting place, and, after the necessary information has been dumped on the reader, a series of events that lead to some sort of change in the protagonist: a change which usually takes place epiphanically, when the story has, to paraphrase Stuart Dybek, shifted from the narrative to the lyrical mode.

There?s nothing wrong with writing stories in this manner; some of the best American fiction follows just such a traditional blueprint. But the Vintage anthology ? which, published in 1994, is starting to feel a bit dated ? suggests that this is pretty much the only way to write a story. While the Scribner book offers more ethnic diversity than the Vintage anthology, it likewise doesn?t put much effort into diversity of narrative approach. To the latter?s credit, it does include work by Junot Diaz, A.M. Homes, and Daniel Orozco, but woefully absent from its pages are David Foster Wallace, Lydia Davis, and Dave Eggers, three of our most stylistically influential authors. As such, the Scribner anthology is pretty much the worst fiction anthology out there. Except for every other anthology.

I?ll also point you to another review of the book that is quite positive. The entirety is below:

David Shields and Matthew Vollmer, eds., Fakes: Shields? ongoing project to smash the support beams of conventional fiction (or maybe just expose them; hard to tell sometimes) clearly led him to help assemble this collection, which is largely made up of parodies of everyday forms of writing. (Jack Pendarvis? ?Our Spring Catalog? brilliantly sends up publishing-speak.) But fiction can?t survive on satire alone?one hopes?and the best stories here thrive on taking their artificial formats and making something sincere from them: Charles Yu?s ?Problems for Self-Study,? Charles McLeod?s ?National Treasures,? Caron A. Levis? ?Permission Slip.?

Source: http://bythefirelight.com/2013/01/04/the-short-story-the-class-room-and-ned-directions-forward-fakes-reviewed-at-larb/

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Vomiting Robot Helps Researchers Understand Norovirus

Jan 5, 2013 7:00am

In a study that could make you lose your own lunch, researchers have created a projectile-vomiting robot to research how far the highly contagious norovirus particles travel when somebody with the illness throws up.

Norovirus causes severe projectile vomiting and diarrhea in those infected for up to three days starting 12 to 48 hours after exposure. The symptoms can last up to 62 hours. On average, someone infected with norovirus spreads it to about seven other people through direct touch or contaminated surfaces and food. The virus sickens as many as 21 million Americans each year, according to the U.S. Centers for Disease Control and Prevention, leading to?70,000 hospitalizations and 800 deaths.

Researchers at the Occupational Hygiene Unit at the Health and Safety Laboratory in Britain created ?Vomiting Larry? to get a better idea of how the virus is able to spread so easily and quickly from person to person.

Vomiting Larry consists of a cylinder body filled with water mixed with florescent liquid, a head with an open mouth, and a pump to shoot the water through the mouth, similar to projectile vomit.

After Larry throws up the florescent water, researchers measure how far the airborne vomit particles travel.

?Under normal lighting, you can only see the main area where Larry actually vomited,? Catherine Makison-Booth, Larry?s creator, told ABC News. ?However, under UV light, you can see the particles spread much further than that ? in excess of three meters.?

That means the area that needs to be sanitized when someone with norovirus throws up is bigger than previously thought.

Earlier studies indicate the virus could live for 12 days or longer in the environment where somebody vomited, so the entire area needs to be cleaned with bleach as soon as possible after the vomiting occurred in order to stem the spread of the illness.

Because norovirus spreads quickly and easily from person to person, it can rapidly infect hundreds of people in a short amount of time.

?It can knock out a whole school, hospital, military base or off-shore rig, and there is currently no vaccine for it, so you really just have to let it run its course,? Makison-Booth said.

Makison-Booth said she doesn?t know of any illness that spreads quite the way norovirus does, because it takes so little for a person to contract it.

?One only needs to ingest 20 to 25 viruses to become ill, compared to the hundreds of viruses it takes to contract influenza,? Makison-Booth told ABC. ?When someone with norovirus vomits once, that?s millions of viruses.?

Norovirus is also resistant to many typical cleaning products, like the kinds generally used to clean kitchens and bathrooms, as well as normal hand sanitizer. In order to really clean up after someone with norovirus throws up, ?bleach is definitely the way to go,? Makison-Booth said.

People infected with norovirus should try to stay away from other people for at least 48 hours after the symptoms stop.

The studies could soon become especially relevant, with news that norovirus cases in England this winter are up 72% from last year, according to the Health Protection Agency, including on ships making transatlantic crossing to the United States.

Source: http://abcnews.go.com/blogs/health/2013/01/05/vomiting-robot-helps-researchers-understand-norovirus/

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Friday, January 4, 2013

Geeky Pets 101: 2 Dog Walking Apps , Dog, Cat and other Pet ...

In May, Fujitsu, a company in Japan released a pedometer for dogs. This isn?t a new concept. The pedometer is on the dog?s collar and transmits pace and mileage to the owner?s smartphone which then can be uploaded to a website. Sound familiar? Sound like the Nike+ iPod app that many of us used with the sensor that attached to our sneakers? Yes, same idea. What makes this pedometer stand out is that it is designed for the dogs. It monitors and records the number of steps they take, as well as signs of shivering and external temperature information, the device enables owners to stay informed about the dog?s regular activity levels, making it easy to detect any changes in their pet?s health.

The downfall: It?s only available in Japan.

So what about us dog lovers in US?
What can we use that may have the same techy, geeky, feel?

While there isn?t a gadget that attaches to our dog?s collar and logs miles to a website or server just yet, there are apps that use our smartphones and the GPS technology to log walks we take with our pups. At the moment, we may not know how much they paced while we were at work or how many miles they logged zooming around while they were at the dog park, we can log our walks with our buddies.

A simple search in the app stores for Android and iPhones brings up several results that track the miles, map it, and allow users to share information to social networks. While they all may seem to do the same thing, how they do it, the design, and usability made two stand out the most to me.

For the iPhone, MapMyDOGWALK is from the makers of iMapMyFITNESS and offers a convenient way of logging dog walks while automatically tracking how many calories are being burned at the time. It?s easy to set up with Twitter and if you want to, your music can play while you?re walking. The map function keeps track of the route taken and syncs it to the MapMyWalk.com website. It also lets users know about any upcoming dog events in the local area that might be worth checking out. MapMyDOGWALK is free to download.

For Android, The Purina Petometer, a free app (also available for iPhone) lets owners upload photos and profile data for up to six dogs and share details and locations of those walks with their Facebook friends. A barking-dog alarm signals when the pre-set duration of the walk is over. The app also lets pet owners set alerts for the next walk time, access pet exercise routines as created by Purina?s animal care experts, and build a calendar of walks, veterinary visits, grooming appointments and other canine commitments. Users can share their walks on Facebook and Twitter to show off just how fit and trim their dog is becoming!

Images from Engadget, Apple, and Google Play

Comments

Source: http://www.petswelcome.com/articles/geeky-pets-101-2-dog-walking-apps.html

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Planets abound: Astronomers estimate that at least 100 billion planets populate the galaxy

Jan. 3, 2013 ? Look up at the night sky and you'll see stars, sure. But you're also seeing planets -- billions and billions of them. At least.

That's the conclusion of a new study by astronomers at the California Institute of Technology (Caltech) that provides yet more evidence that planetary systems are the cosmic norm. The team made their estimate while analyzing planets orbiting a star called Kepler-32 -- planets that are representative, they say, of the vast majority in the galaxy and thus serve as a perfect case study for understanding how most planets form.

"There's at least 100 billion planets in the galaxy -- just our galaxy," says John Johnson, assistant professor of planetary astronomy at Caltech and coauthor of the study, which was recently accepted for publication in the Astrophysical Journal. "That's mind-boggling."

"It's a staggering number, if you think about it," adds Jonathan Swift, a postdoc at Caltech and lead author of the paper. "Basically there's one of these planets per star."

The planetary system in question, which was detected by the Kepler space telescope, contains five planets. The existence of two of those planets have already been confirmed by other astronomers. The Caltech team confirmed the remaining three, then analyzed the five-planet system and compared it to other systems found by the Kepler mission.

The planets orbit a star that is an M dwarf -- a type that accounts for about three-quarters of all stars in the Milky Way. The five planets, which are similar in size to Earth and orbit close to their star, are also typical of the class of planets that the telescope has discovered orbiting other M dwarfs, Swift says. Therefore, the majority of planets in the galaxy probably have characteristics comparable to those of the five planets.

While this particular system may not be unique, what does set it apart is its coincidental orientation: the orbits of the planets lie in a plane that's positioned such that Kepler views the system edge-on. Due to this rare orientation, each planet blocks Kepler -32's starlight as it passes between the star and the Kepler telescope.

By analyzing changes in the star's brightness, the astronomers were able to determine the planets' characteristics, such as their sizes and orbital periods. This orientation therefore provides an opportunity to study the system in great detail -- and because the planets represent the vast majority of planets that are thought to populate the galaxy, the team says, the system also can help astronomers better understand planet formation in general.

"I usually try not to call things 'Rosetta stones,' but this is as close to a Rosetta stone as anything I've seen," Johnson says. "It's like unlocking a language that we're trying to understand -- the language of planet formation."

One of the fundamental questions regarding the origin of planets is how many of them there are. Like the Caltech group, other teams of astronomers have estimated that there is roughly one planet per star, but this is the first time researchers have made such an estimate by studying M-dwarf systems, the most numerous population of planets known.

To do that calculation, the Caltech team determined the probability that an M-dwarf system would provide Kepler-32's edge-on orientation. Combining that probability with the number of planetary systems Kepler is able to detect, the astronomers calculated that there is, on average, one planet for every one of the approximately 100 billion stars in the galaxy. But their analysis only considers planets that are in close orbits around M dwarfs -- not the outer planets of an M-dwarf system, or those orbiting other kinds of stars. As a result, they say, their estimate is conservative. In fact, says Swift, a more accurate estimate that includes data from other analyses could lead to an average of two planets per star.

M-dwarf systems like Kepler-32's are quite different from our own solar system. For one, M dwarfs are cooler and much smaller than the sun. Kepler-32, for example, has half the mass of the sun and half its radius. The radii of its five planets range from 0.8 to 2.7 times that of Earth, and those planets orbit extremely close to their star. The whole system fits within just over a tenth of an astronomical unit (the average distance between Earth and the sun) -- a distance that is about a third of the radius of Mercury's orbit around the sun. The fact that M-dwarf systems vastly outnumber other kinds of systems carries a profound implication, according to Johnson, which is that our solar system is extremely rare. "It's just a weirdo," he says.

The fact that the planets in M-dwarf systems are so close to their stars doesn't necessarily mean that they're fiery, hellish worlds unsuitable for life, the astronomers say. Indeed, because M dwarfs are small and cool, their temperate zone -- also known as the "habitable zone," the region where liquid water might exist -- is also further inward. Even though only the outermost of Kepler-32's five planets lies in its temperate zone, many other M dwarf systems have more planets that sit right in their temperate zones.

As for how the Kepler-32 system formed, no one knows yet. But the team says its analysis places constraints on possible mechanisms. For example, the results suggest that the planets all formed farther away from the star than they are now, and migrated inward over time.

Like all planets, the ones around Kepler-32 formed from a proto-planetary disk -- a disk of dust and gas that clumped up into planets around the star. The astronomers estimated that the mass of the disk within the region of the five planets was about as much as that of three Jupiters. But other studies of proto-planetary disks have shown that three Jupiter masses can't be squeezed into such a tiny area so close to a star, suggesting to the Caltech team that the planets around Kepler-32 initially formed farther out.

Another line of evidence relates to the fact that M dwarfs shine brighter and hotter when they are young, when planets would be forming. Kepler-32 would have been too hot for dust -- a key planet-building ingredient -- to even exist in such close proximity to the star. Previously, other astronomers had determined that the third and fourth planets from the star are not very dense, meaning that they are likely made of volatile compounds such as carbon dioxide, methane, or other ices and gases, the Caltech team says. However, those volatile compounds could not have existed in the hotter zones close to the star.

Finally, the Caltech astronomers discovered that three of the planets have orbits that are related to one another in a very specific way. One planet's orbital period lasts twice as long as another's, and the third planet's lasts three times as long as the latter's. Planets don't fall into this kind of arrangement immediately upon forming, Johnson says. Instead, the planets must have started their orbits farther away from the star before moving inward over time and settling into their current configuration.

"You look in detail at the architecture of this very special planetary system, and you're forced into saying these planets formed farther out and moved in," Johnson explains.

The implications of a galaxy chock full of planets are far-reaching, the researchers say. "It's really fundamental from an origins standpoint," says Swift, who notes that because M dwarfs shine mainly in infrared light, the stars are invisible to the naked eye. "Kepler has enabled us to look up at the sky and know that there are more planets out there than stars we can see."

In addition to Swift and Johnson, the other authors on the Astrophysical Journal paper are Caltech graduate students Timothy Morton and Benjamin Montet; Caltech postdoc Philip Muirhead; former Caltech postdoc Justin Crepp of the University of Notre Dame; and Caltech alumnus Daniel Fabrycky (BS '03) of the University of Chicago. The title of the paper is, "Characterizing the cool KOIS IV: Kepler-32 as a prototype for the formation of compact planetary systems throughout the galaxy." In addition to using Kepler, the astronomers made observations at the W. M. Keck Observatory and with the Robo-AO system at Palomar Observatory. Support for all of the telescopes was provided by the W. M. Keck Foundation, NASA, Caltech, the Inter-University Centre for Astronomy and Astrophysics, the National Science Foundation, the Mt. Cuba Astronomical Foundation, and Samuel Oschin.

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Story Source:

The above story is reprinted from materials provided by California Institute of Technology. The original article was written by Marcus Woo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Jonathan J. Swift, John Asher Johnson, Timothy D. Morton, Justin R. Crepp, Benjamin T. Montet, Daniel C. Fabrycky, Philip S. Muirhead. Characterizing the Cool KOIs IV: Kepler-32 as a prototype for the formation of compact planetary systems throughout the Galaxy. Astrophysical Journal, 2012; (submitted) [link]

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/9-j2mUpl-FM/130103143422.htm

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Signal Advertising Manual For The Yoga Business | Cheap ...

Most yoga studios are situated within strip centers and fitness centers, so using storefront signage can be an effective way to promote. Fascinating indicators will cause them to become come inside and sign-up for a class get the attention of passers-by, and hopefully. In addition, using car symptoms can be beneficial for yoga studios. Though most don?t have an actual navy car, the employees? personal cars may be used to produce vehicle symptoms and increase the business.Banner AdvertisingPromote your studio?s grand opening, new courses, and specific school discounts by utilizing dangling a big plastic advertising over your entry. Keep your message short and to-the-point, utilizing a single artwork (or two, if necessary) to prevent consuming the message. Style your advertising by having an emphasis on the conditioning and lean build a discipline like yoga provides. Use frequent yoga poses and peaceful colors plot prospective students and receive them into your storefront. Remember that the banner has to be read from a distance, so use contrasting colors and create the writing as large as possible.Window AdvertisingThere are many different services and products to use on your own yoga studio windows. If you?d like to cover the windows in their whole, use one-way vision artwork. This substance is perforated and see-through, so you can present a full-color advertisement without limiting the visibility to the outside. Your courses will take advantage of the day light streaming in through the windows, but potential prospects will still see everything you need to offer. Use vinyl decals for smaller window design which record your lasting data (name, school situations, etc.), and use window clings (which don?t have adhesive) for temporary promotions.Mobile AdvertisingAlthough yoga studios typically do not have a business vehicle, employees? individual vehicles are often used for running errands and traveling to distant sessions. Do not overlook this great opportunity for cellular marketing! Your workers might be worried about marketing the business on their private car, so a car magnet is a superb option as it can simply be removed and reapplied. Your magnets must record your studio name, telephone number, and site when you yourself have one. If you do have a fleet vehicle or are okay with using more-permanent signage, contemplate a window decal on your vehicle?s back window, which offers lots of space to display more-detailed information about your studio.The point of yoga studio advertising is to determine your business a superior option for exercise. Reaching new clients and building brand recognition will not happen immediately, but signs are a good, economical method to start the method.

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Source: http://taxcruncher.co.uk/signal-advertising-manual-for-the-yoga-business/

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Comprehensive Information On Precious Metal IRA In | Liberty

Gold has been used for thousands of years as a safe and enduring store of worth. During these unpredictable financial times, it has again come forth as a primary asset and may actually be the perfect investment option. Let?s do a comparison of gold with the asset classes which most often consist a pension program. Stocks, bonds, and savings accounts all depend upon the performance of a different establishment or individual for value. Gold however, does not. This characteristic by itself causes it to become among the best assets to keep for investment protection.

There are numerous strategies to making investments in this precious metal like obtaining gold bars, coins, gold ETFs, and gold mutual funds. Gold bullion coins are often thought of as fairly treasured because they may also be collectors? items. Their value does not only come because of their ounces, but also their rarity.

Even though acquiring gold might be very simple, 401k gold investment is a bit more complicated. The Tax Payer Relief Act passed fifteen years ago permits people to incorporate rare metals, for example gold, as a part of their retirement plans. While you?ll be able to make use of a 401k in order to get hold of gold investments, you will probably not be able to do this with a standard 401k plan.

Most company-subsidized 401k plans have polices regarding the types of assets which could be purchased in the program. Hence, it?s generally a prerequisite that someone should first rollover the existing 401k program into gold 401k. Only then can they have the capacity to start investing in precious metals.

As a note, 401k gold is actually a gold Individual Retirement Account which has been backed by the previous 401k. The only way to personally own gold as an asset is by means of the gold IRA.

If you need to make investments in a gold Individual Retirement Account, having guidance from professional people would be necessary. You may reach them online because of the present technologies. For details, check out IRAToGold.net

Source: http://dwiminneapolis.com/finance/comprehensive-information-on-precious-metal-ira-in/

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Thursday, January 3, 2013

Secure communication technology can conquer lack of trust

Jan. 2, 2013 ? Many scenarios in business and communication require that two parties share information without either being sure if they can trust the other. Examples include secure auctions and identification at ATM machines. Exploiting the strange properties of the quantum world could be the answer to dealing with such distrust: researchers at the Centre for Quantum Technologies (CQT) at the National University of Singapore have used the quantum properties of light to perform the world's first demonstration of a 'secure bit commitment' technology.

The work is described in Nature Communications.

Secure bit commitment is equivalent to making a sealed bid in an auction. One party, usually known as Alice, 'commits' some information (a bit) to another party, usually known as Bob, with Alice later choosing when to reveal that bit. A bit commitment protocol is secure if Bob can't learn anything about the bit until Alice reveals it, and if Alice can't change the bit between committing and revealing it.

Compare this with a sealed-bid auction: the bidder must commit to an amount they will pay, and they should remain the only one who knows what the amount is until all the bids are revealed. This is desirable, because a dishonest auctioneer or anyone who accessed the information early could influence the bidding. At the same time, we want to make sure that the bidder cannot change the bid depending on any news he receives later on. This means that we cannot simply solve the problem by allowing the bidder to keep hold of their bid, because they might be dishonest and change the amount.

Traditional solutions to this problem -- think sealed envelopes or data held by a third party -- always depend on trust. Indeed, it has been proven that with classical information alone there is no solution that can totally protect the bidder and the bid receiver from unscrupulous behaviour.

In the demonstration, Alice communicates with Bob using photons, the particles of light. Alice creates pairs of photons that have the quantum property of being entangled, meaning that the photons' properties are connected even when they are separated. Alice splits each pair, keeping one photon and sending its entangled partner to Bob.

Alice encodes her 'bid' in her photons in such a way that Bob can only access the bid when Alice gives him instructions to decode his photons. But Bob can learn enough from his photons beforehand to know whether Alice is trying to cheat when she sends the instructions, say by using a different decoding. This way, both parties are protected from dishonesty.

The experiments were led by two Principal Investigators at CQT: Stephanie Wehner, who had earlier proposed a key theoretical requirement for secure bit commitment, and Christian Kurtsiefer, whose experimental group has expertise in creating entangled photons pair.

Wehner's idea was that secure bit commitment is possible with just one realistic, physical assumption: that anyone trying to cheat has limited ability to store quantum photons. (The quantum entanglement isn't enough on its own.) She proposed and developed this idea of 'noisy storage' in earlier papers.

"I wanted to demonstrate that secure bit commitment with the noisy storage model can work in the real world," says Wehner. With the experimental support from Kurtsiefer's group, it did. The team's Alice and Bob used 250,000 pairs of entangled photons to commit a bit secure against a memory of 972 quantum bits suffering a certain noise. Quantum memories aren't even that big today, but if they got better, security could be restored by increasing the number of photons. The demonstration is a proof-of-principle that points towards a possible quantum technology for secure communication in our future.

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Story Source:

The above story is reprinted from materials provided by Centre for Quantum Technologies at the National University of Singapore, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Nelly Huei Ying Ng, Siddarth K. Joshi, Chia Chen Ming, Christian Kurtsiefer, Stephanie Wehner. Experimental implementation of bit commitment in the noisy-storage model. Nature Communications, 2012; 3: 1326 DOI: 10.1038/ncomms2268

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/computers_math/information_technology/~3/gNIRNRMeLsg/130102115540.htm

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